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C88.20

✓ Billable

Heavy chain disease not having achieved remission

Neoplasms (C00-D49)

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Also Known As

Franklin disease NOSFranklin disease not having achieved remissionFranklin disease with failed remissionGamma heavy chain disease NOSGamma heavy chain disease not having achieved remissionGamma heavy chain disease with failed remissionHeavy chain disease NOSHeavy chain disease with failed remissionMu heavy chain disease not having achieved remissionMu heavy chain disease NOSMu heavy chain disease not having achieved remissionMu heavy chain disease with failed remission

❌ Excludes1

inherited

Rules inherited from parent codes in the hierarchy.

C88
  • • B-cell lymphoma, unspecified (C85.1-)
  • • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Clinical Description

ICD-10-CM code C88.20 represents heavy chain disease not having achieved remission. This code falls under the Neoplasms (C00-D49) classification. It is a billable/specific code valid for HIPAA-covered transactions as of October 1, 2025 (FY2026). This code can be used to indicate a diagnosis for reimbursement purposes on insurance claims.

This is a 6-character code at the 5th level of specificity. This is the most specific code available in this subcategory. Coders should note that C88.20 has 2 Excludes1 restriction(s) — codes that cannot be reported together on the same claim.

Frequently Asked Questions

What is ICD-10 code C88.20?

ICD-10-CM code C88.20 is "Heavy chain disease not having achieved remission". It belongs to the category: Neoplasms (C00-D49).

Is C88.20 a billable ICD-10 code?

Yes, C88.20 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What codes are excluded with C88.20?

C88.20 has 2 Excludes1 rule(s). These codes are mutually exclusive and cannot be coded together on the same claim.

Related Codes in C88.2

Other codes in the same category that may be relevant for differential coding:

C88.21Heavy chain disease, in remission

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Code Information

CodeC88.20
BillableYes
ParentC88.2
CategoryNeoplasms (C00-D49)
Excludes12 rule(s)
Excludes20 note(s)

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)