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D61.81

⚠ Non-billable (Header)

Pancytopenia

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

⚠️ This is a category header code — not billable. Use a more specific child code below.

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❌ Excludes1

direct

Cannot be coded with D61.81

  • • pancytopenia (due to) (with) aplastic anemia (D61.9)
  • • pancytopenia (due to) (with) bone marrow infiltration (D61.82)
  • • pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
  • • pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
  • • pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
  • • pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
  • • pancytopenia (due to) (with) myeloproliferative disease (D47.1)

⚠️ Excludes2

direct

May be coded together if both conditions coexist

  • • pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)

Child Codes (3)

D61.810Antineoplastic chemotherapy induced pancytopeniaD61.811Other drug-induced pancytopeniaD61.818Other pancytopenia

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Code Information

CodeD61.81
BillableNo — Header code
ParentD61.8
CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Excludes17 rule(s)
Excludes21 note(s)
Child codes3

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)