D81.82
✓ BillableActivated Phosphoinositide 3-kinase Delta Syndrome [APDS]
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Also Known As
p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
✅ No additional coding notes for D81.82
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CodeD81.82
BillableYes
ParentD81.8
CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Excludes10 rule(s)
Excludes20 note(s)
Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)