E53.1
✓ BillablePyridoxine deficiency
Endocrine, nutritional and metabolic diseases (E00-E89)
Also Known As
❌ Excludes1
directThese codes are mutually exclusive. Never code them together.
- • pyridoxine-responsive sideroblastic anemia (D64.3)
❌ Excludes1
inheritedRules inherited from parent codes in the hierarchy.
- • sequelae of vitamin B deficiency (E64.8)
Clinical Description
ICD-10-CM code E53.1 represents pyridoxine deficiency. This code falls under the Endocrine, nutritional and metabolic diseases (E00-E89) classification. It is a billable/specific code valid for HIPAA-covered transactions as of October 1, 2025 (FY2026). This code can be used to indicate a diagnosis for reimbursement purposes on insurance claims.
This is a 5-character code at the 4th level of specificity. This is the most specific code available in this subcategory. Coders should note that E53.1 has 2 Excludes1 restriction(s) — codes that cannot be reported together on the same claim.
Frequently Asked Questions
What is ICD-10 code E53.1?
ICD-10-CM code E53.1 is "Pyridoxine deficiency". It belongs to the category: Endocrine, nutritional and metabolic diseases (E00-E89).
Is E53.1 a billable ICD-10 code?
Yes, E53.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
What codes are excluded with E53.1?
E53.1 has 2 Excludes1 rule(s). These codes are mutually exclusive and cannot be coded together on the same claim.
Related Codes in E53
Other codes in the same category that may be relevant for differential coding:
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Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)