T80.51XD
✓ BillableAnaphylactic reaction due to administration of blood and blood products, subsequent encounter
Injury, poisoning and certain other consequences of external causes (S00-T88)
❌ Excludes1
inheritedRules inherited from parent codes in the hierarchy.
- • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- • allergic reaction or shock NOS (T78.2)
- • anaphylactic reaction or shock NOS (T78.2)
- • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- • other serum reaction (T80.6-)
⚠️ Excludes2
inheritedRules inherited from parent codes.
- • bone marrow transplant rejection (T86.01)
- • febrile nonhemolytic transfusion reaction (R50.84)
- • fluid overload due to transfusion (E87.71)
- • posttransfusion purpura (D69.51)
- • transfusion associated circulatory overload (TACO) (E87.71)
- • transfusion (red blood cell) associated hemochromatosis (E83.111)
- • transfusion related acute lung injury (TRALI) (J95.84)
Clinical Description
ICD-10-CM code T80.51XD represents anaphylactic reaction due to administration of blood and blood products, subsequent encounter. This code falls under the Injury, poisoning and certain other consequences of external causes (S00-T88) classification. It is a billable/specific code valid for HIPAA-covered transactions as of October 1, 2025 (FY2026). This code can be used to indicate a diagnosis for reimbursement purposes on insurance claims.
This is a 8-character code at the 7th level of specificity. This is the most specific code available in this subcategory. Coders should note that T80.51XD has 5 Excludes1 restriction(s) — codes that cannot be reported together on the same claim.
Frequently Asked Questions
What is ICD-10 code T80.51XD?
ICD-10-CM code T80.51XD is "Anaphylactic reaction due to administration of blood and blood products, subsequent encounter". It belongs to the category: Injury, poisoning and certain other consequences of external causes (S00-T88).
Is T80.51XD a billable ICD-10 code?
Yes, T80.51XD is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
What codes are excluded with T80.51XD?
T80.51XD has 5 Excludes1 rule(s). These codes are mutually exclusive and cannot be coded together on the same claim.
Can T80.51XD be coded with other codes?
T80.51XD has 7 Excludes2 note(s). These conditions can be coded together if both are documented in the patient record.
Related Codes in T80.51
Other codes in the same category that may be relevant for differential coding:
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Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)