Z15

⚠ Non-billable (Header)

Genetic susceptibility to disease

Factors influencing health status and contact with health services (Z00-Z99)

⚠️ This is a category header code — not billable. Use a more specific child code below.

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ℹ️ Includes

  • confirmed abnormal gene

❌ Excludes1

direct

These codes are mutually exclusive. Never code them together.

  • chromosomal anomalies (Q90-Q99)

📋 Code Instructions

direct
  • code, if applicable, for any associated family history of the disease (Z80-Z84)

Clinical Description

ICD-10-CM code Z15 represents genetic susceptibility to disease. This code falls under the Factors influencing health status and contact with health services (Z00-Z99) classification. It is a non-billable category header code. A more specific child code from the list below must be used for billing and reimbursement purposes.

Frequently Asked Questions

What is ICD-10 code Z15?

ICD-10-CM code Z15 is "Genetic susceptibility to disease". It belongs to the category: Factors influencing health status and contact with health services (Z00-Z99).

Is Z15 a billable ICD-10 code?

No, Z15 is a non-billable header code. A more specific child code must be used for billing.

What codes are excluded with Z15?

Z15 has 1 Excludes1 rule(s). These codes are mutually exclusive and cannot be coded together on the same claim.

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Code Information

CodeZ15
BillableNo — Header code
CategoryFactors influencing health status and contact with health services (Z00-Z99)
Excludes11 rule(s)
Excludes20 note(s)
Child codes5

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)