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Z16

⚠ Non-billable (Header)

Resistance to antimicrobial drugs

Factors influencing health status and contact with health services (Z00-Z99)

⚠️ This is a category header code — not billable. Use a more specific child code below.

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📋 Code Instructions

  • • Code first: the infection

❌ Excludes1

direct

Cannot be coded with Z16

  • • Methicillin resistant Staphylococcus aureus infection (A49.02)
  • • Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
  • • Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)

Child Codes (3)

Z16.1Resistance to beta lactam antibioticsZ16.2Resistance to other antibioticsZ16.3Resistance to other antimicrobial drugs

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Code Information

CodeZ16
BillableNo — Header code
CategoryFactors influencing health status and contact with health services (Z00-Z99)
Excludes13 rule(s)
Excludes20 note(s)
Child codes3

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)