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Z79.621

✓ Billable

Long term (current) use of calcineurin inhibitor

Factors influencing health status and contact with health services (Z00-Z99)

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Also Known As

Long term (current) use of cyclosporineLong term (current) use of tacrolimus

⚠️ Excludes2

inherited

Rules inherited from parent codes.

Z79.6
  • • long term (current) use of steroids (Z79.5-)
  • • long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)
Z79
  • • drug abuse and dependence (F11-F19)
  • • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)

Clinical Description

ICD-10-CM code Z79.621 represents long term (current) use of calcineurin inhibitor. This code falls under the Factors influencing health status and contact with health services (Z00-Z99) classification. It is a billable/specific code valid for HIPAA-covered transactions as of October 1, 2025 (FY2026). This code can be used to indicate a diagnosis for reimbursement purposes on insurance claims.

This is a 7-character code at the 6th level of specificity. This is the most specific code available in this subcategory.

Frequently Asked Questions

What is ICD-10 code Z79.621?

ICD-10-CM code Z79.621 is "Long term (current) use of calcineurin inhibitor". It belongs to the category: Factors influencing health status and contact with health services (Z00-Z99).

Is Z79.621 a billable ICD-10 code?

Yes, Z79.621 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

Can Z79.621 be coded with other codes?

Z79.621 has 4 Excludes2 note(s). These conditions can be coded together if both are documented in the patient record.

Related Codes in Z79.62

Other codes in the same category that may be relevant for differential coding:

Z79.620Long term (current) use of immunosuppressive biologicZ79.622Long term (current) use of Janus kinase inhibitorZ79.623Long term (current) use of mammalian target of rapamycin (mTOR) inhibitorZ79.624Long term (current) use of inhibitors of nucleotide synthesis

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Code Information

CodeZ79.621
BillableYes
ParentZ79.62
CategoryFactors influencing health status and contact with health services (Z00-Z99)
Excludes10 rule(s)
Excludes24 note(s)

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)