D57.4
⚠ Non-billable (Header)Sickle-cell thalassemia
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
⚠️ This is a category header code — not billable. Use a more specific child code below.
Also Known As
Sickle-cell beta thalassemiaThalassemia Hb-S disease
❌ Excludes1
inherited from D57Rules from parent category D57: Sickle-cell disorders
- • other hemoglobinopathies (D58.-)
📋 Code Instructions
from D57- • code for any associated fever (R50.81)
Child Codes (6)
D57.40Sickle-cell thalassemia without crisisD57.41Sickle-cell thalassemia, unspecified, with crisisD57.42Sickle-cell thalassemia beta zero without crisisD57.43Sickle-cell thalassemia beta zero with crisisD57.44Sickle-cell thalassemia beta plus without crisisD57.45Sickle-cell thalassemia beta plus with crisis
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CodeD57.4
BillableNo — Header code
ParentD57
CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Excludes11 rule(s)
Excludes20 note(s)
Child codes6
Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)