D57.453
✓ BillableSickle-cell thalassemia beta plus with cerebral vascular involvement
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Also Known As
HbS-beta plus with cerebral vascular involvementSickle-cell beta plus with cerebral vascular involvement
✅ No additional coding notes for D57.453
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CodeD57.453
BillableYes
ParentD57.45
CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Excludes10 rule(s)
Excludes20 note(s)
Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)