D57.459

✓ Billable

Sickle-cell thalassemia beta plus with crisis, unspecified

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Also Known As

HbS-beta plus with crisis with unspecified complicationSickle-cell beta plus with crisis with unspecified complicationSickle-cell thalassemia beta plus with (painful) crisis NOSSickle-cell thalassemia beta plus with (vaso-occlusive) pain NOS

✅ No additional coding notes for D57.459

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Code Information

CodeD57.459

BillableYes

ParentD57.45

CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Excludes10 rule(s)

Excludes20 note(s)

Data Source

CMS ICD-10-CM 2026 Tabular List

Updated October 1, 2025 (FY2026)