D89
⚠ Non-billable (Header)Other disorders involving the immune mechanism, not elsewhere classified
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
⚠️ This is a category header code — not billable. Use a more specific child code below.
❌ Excludes1
directCannot be coded with D89
- • hyperglobulinemia NOS (R77.1)
- • monoclonal gammopathy (of undetermined significance) (D47.2)
⚠️ Excludes2
directMay be coded together if both conditions coexist
- • transplant failure and rejection (T86.-)
Child Codes (7)
D89.0Polyclonal hypergammaglobulinemiaD89.1CryoglobulinemiaD89.2Hypergammaglobulinemia, unspecifiedD89.3Immune reconstitution syndromeD89.4Mast cell activation syndrome and related disordersD89.8Other specified disorders involving the immune mechanism, not elsewhere classifiedD89.9Disorder involving the immune mechanism, unspecified
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CodeD89
BillableNo — Header code
CategoryDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Excludes12 rule(s)
Excludes21 note(s)
Child codes7
Data Source
CMS ICD-10-CM 2026 Tabular List
Updated October 1, 2025 (FY2026)